topiramate Indications and Usage

Indications and Usage

 

FDA Approved Indications

Off-Label Uses

Migraine

Neuropathic Pain

Epilepsy Monotherapy

Chronic Pain, Fibromyalgia

Epilepsy Adjunctive Therapy

Bipolar Disorder

Weight Loss and Obesity

Depression

 

Obsessive Compulsive Disorder

 

Post-Traumatic Stress Disorder

 

Borderline Personality Disorder

 

Alcohol Dependency and Addiction

 

Cocaine Addiction

 

Methamphetamine Addiction

 

FDA Approved Indications

 

Monotherapy in Epilepsy

Topamax (topiramate) Tablets and Topamax (topiramate capsules) Sprinkle Capsules are FDA approved and indicated as monotherapy in children and adolescents age 10 years and older and for adults with partial onset seizures or primary generalized tonic-clonic seizures.  This means that the FDA has approved topiramate to be used as initial or first line treatment and without any other anti-epileptic medication (monotherapy).

 

Adjunctive Therapy in Epilepsy

Topamax (topiramate) Tablets and Topamax (topiramate capsules) Sprinkle Capsules are FDA approved and indicated as adjunctive therapy for adults and for pediatric patients age 2 years to 16 years with partial onset seizures or primary generalized tonic-clonic seizures and in patients 2 years of age and older with seizures associated with Lennox-Gastaut syndrome.  This means that the FDA has approved topiramate to be used as add-on therapy to another FDA approved anti-epileptic medication (adjunctive therapy) for patients who have failed to respond to monotherapy with the original anti-epileptic medication.

 

Migraine Headaches

Topamax (topiramate) Tablets and Topamax (topiramate capsules) Sprinkle Capsules are FDA approved and indicated for adults for prophylaxis of migraine headache.  This means that topiramate is used as a preventive medication for migraine headaches to make the headaches less frequent, less severe, and of shorter duration.  Topiramate is not intended to be used as an abortive medication to treat an acute migraine attack.

 

Weight Loss and Obesity

The United States FDA approved Qsymia (phentermine and topiramate extended-release) to be prescribed in addition to a reduced-calorie diet and regular exercise for weight loss and chronic management of obesity.  Qsymia (phentermine and topiramate extended-release) is approved for usage in adults who are obese with a body mass index (BMI) of 30 or greater or for adults who are overweight with a body mass index (BMI) of 27 or greater who have at least one weight-related complication such as type 2 diabetes mellitus, high cholesterol (dyslipidemia, hyperlipidemia), or high blood pressure (hypertension).

 

topiramate Overview topiramate Side Effects and Adverse Reactions

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